FENTANYL OVERDOSE SYMPTOMS AND DURATION OPTIONS

Istradefylline 40 mg/working day amplified peak levels and AUC of CYP3A4 substrates in clinical trials. This effect was not observed with istradefylline twenty mg/day. Consider dose reduction of sensitive CYP3A4 substrates.If coadministration of CYP3A4 inhibitors with fentanyl is necessary, watch patients for respiratory depression and sedation at